Address
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Dr. P. T. Perumal
Scientist G and Head
Organic Chemistry Division
Central Leather Research Institute
Adyar, Chennai – 600 020
e-mail:ptperumal@gmail.com
Tel: 91-44-24913289
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| Marital
status |
Married |
| Nationality |
Indian |
| Age & Date of Birth
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55yrs, 06-Mar-1951 |
| Date of joining CSIR : |
20 - 02 – 1985 as Scientist-C (IICT) |
| Research Experience and Area of Specialization |
27 years in the field of synthetic , organic chemistry and medicinal Chemistry.
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| RESEARCH PROGRAM |
Recent years have seen renewed interest in safer leather chemicals like biocides, tanning agents, dyes and pigments due to increased public awareness about the environmental issues, toxicity of synthetic compounds and their intermediates during manufacture and usage, the growing preference for cleaner technologies and the Government legislation on toxic waste disposal etc. This has necessitated processing industries like textile, leather, wool, food and pharmaceutical to look for viable natural or synthetic chemicals that are non-toxic / less toxic compared to the existing ones. Accordingly. The principle of organic leather manufacture is a commitment to the eco system wherein quality leathers are produced by using nontoxic and less toxic natural products without causing environmental deterioration. To achieve this goal we are working on the development of leather chemicals like tanning agents, preservatives, colorants etc from plant sources as raw materials. Studies are also being carried out to develop safer leather chemicals through novel synthetic routes and methodologies.
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| MAJOR ACHIEVEMENTS |
| 1.Technology development : |
- A Microprocessor controlled technology for the manufacture of blended vegetable tannin extract from babul bark, myrobalan nuts and wattle bark had been released to Rallis India Ltd. The process is commercialized .
- The process for the manufacture of a blended vegetable tannin extract based on cashew testa, myrobalan nuts and wattle bark was developed and successfully demonstrated to the sponsor M/S. Laxmi Starch Ltd., The party had started commercial production of the extract.
- The know-how for the preparation of gallic acid from myrobalan nuts and
3,4,5-trimethoxy benzoic acid (a pharmaceutical intermediate) from gallic
acid was developed and demonstrated to M/S. Silver Hill Chemicals Ltd.
- Process for PCP substitutes like TCMTB and OITZ has been developed.
- Process for the extraction and formulation of natural dyes and pigments
suitable for fashion leathers has been standardized. 3.
- Technical know-how for preparation of a substituted triazole compound, an
agrochemical intermediate, has been released to Nagarjuna Agro Chem. Ltd.
Hyderabad. Duration : 3 years
- Technical know-how for preparation of pharmaceutical intermediates has been released
Tagros Chemicals Ltd. Chennai. Duration : 2 years.
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| 2. Basic research : |
- Biocides based on Vilsmeier and Diels-Alder-adducts are available for valuation.
- Process for the preparation of syntans having light resistance and filling
characteristics have been developed at laboratory level.
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| 3. Patents : |
- A novel process for the preparation of eco-friendly black colourant for leather from myrobalan sludge has been patented.(Indian Patent Application No. 1868DEL97).
- A process for the preparation of plant based (Punica granatum) acrylate complex has been patented. (Indian Patent Aplication No. 1057DEL2001).
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| 4. Publications : |
- More than 180 papers were published in national and international journals during the last 7 years with high impact factors.
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| 5. HRD : |
- 18 Research students from this division were awarded Ph.D.degrees till date.
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| 6. Societal benefits : |
- A better method of collection, grading and storage of myrobalan nuts has been evolved. Tribals of Andhra Pradesh, Tamil Nadu and Madhya Pradesh engaged in collection of minor forest produce were given training through Tribal Development Corporations on the above aspects, which has augumented their income.
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| Visits Abroad |
- PDF (Organic Chemistry) in the year 1981-1983 in Purdue University, USA.
with Prof. H. C. Brown (Nobel Laureate)
- Visiting Scientist in the year 1989-1991 in Univesity of Miami, USA. and
Univrsity of Florida, USA.
- Inivited Lecture in the year 2001 National University of
Singapore, Singapore
- Distinguished Visitor in the year 2005 in University of Complutense,
Madrid, Spain
- Visiting Professor in the year 2007 in University of Oklahoma, USA
- Distinguished Visitor in the year 2008 in University of Complutense,
Madrid, Spain
- Deliverd lecture on "Green Chemistry Approach to Synthesis Heterocyclic and polymeric Compounds" at Singapore International Chemical Conference, Singapore, December 2009.
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| Research Publications |
- 196 in peer reviewed international journals
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| Research Guidance (Ph. D) |
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| Teaching Experience |
- 25 years ( M.Sc. and M.Tech. )
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| Technical Know-how |
- Four products into Nagarjuna Agrochemicals, Hyderabad & Two products for Tagros,chennai
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| List of students received Ph.D. degree |
- Title of thesis: Synthetic studies on Vilsmeier reagent and synthesis of spirocyclic
diketone related to Fredericamycin A
Name: M. Venugopal
University: University of Madras
Discipline: Chemistry
Year: 1992
Comments: Highly commended
- Title of thesis: New methods in the synthesis of isoxazoles, isoxazolines, oxazines, oxazolidinones and analogous Systems
Name: B. Balasundaram
University: University of Madras
Discipline: Chemistry
Year: 1992
Comments: Highly commended
- Title of thesis: Synthetic applications of Vilsmeier reagent: Novel methods for the construction of nitrogen based heterocycles
Name: V. J. Majo
University: University of Madras
Discipline: Chemistry
Year: 1997
Comments: Highly commended
- Title of thesis: Novel routes to the synthesis of nitrogen and oxygen based heterocycles
by Vilsmeier reagent
Name: R. R. Amaresh
University: University of Madras
Discipline: Chemistry
Year: 1998
Comments: Highly commended
- Title of Thesis: Synthesis of substituted quinolines, phenanthridines, azabicycloalkanones through Diels-Alder reaction promoted by Indium trichloride
Name: G. Babu
University: University of Madras
Discipline: Chemistry
Year: 1998
Comments: Highly commended
- Title of thesis: Synthetic applications of Vilsmeier reagent: Synthesis of carbocyclic, heterocyclic compounds and vinamidinium salts
Name: S. Selvi
University: University of Madras
Discipline: Chemistry
Year: 2000
Comments: Commended
- Title of thesis: Synthesis of nitrogen based heterocylces-quinolines, indoles, carbazoles
and carboline derivatives
Name: R. Nagarajan
University: University of Madras
Discipline: Chemistry
Year: 2003
Comments: Highly commended
- Title of thesis: Synthesis, characterisation and antimicrobial properties of imidazolidine-
2,4-diones, vicinal diamines, bisamides, thiosemicarbazones, 1,3,4-thiadiazolines and
1,2,4-triazines
Name: S. Thennarasu
University: University of Madras
Discipline: Chemistry
Year: 2003
Comments: Highly commended
- Title of thesis: Studies on nitrogen and oxygen containing heterocycles: synthesis of substituted quinolines, chromanoquinolines, pyridines, benzopyrans and xanthenes
Name:M. Anniyappan
University: University of Madras
Discipline: Chemistry
Year: 2003
Comments: Highly commended
- Title of thesis: Analytical application of spectrophotometry,
spectrofluorimetry and HPLC for the determination of hexamine and its
pharmaceutical formulation
Name: M. Balasubramanian
University: University of Madras
Discipline: Chemistry
Year: 2003
Comments: Highly commended
- Title of thesis: Synthesis of novel heterocycles: Pyrazoles, benzimidazoles, pyrazolyl dihydropyridines and pyrazolyl tetrahydroquinolines
Name: R. Sridhar
University: University of Madras
Discipline: Chemistry
Year: 2004
Comments: Highly commended
- Title of thesis: Syntheses and reactions of 3,4-dihydropyrimidin-2(1H)-one scaffolds.
Oxidative coupling of active methylene compounds on α,β-unsaturated systems and
imines.
Name: P. Shanmugam
University: University of Madras
Discipline: Chemistry
Year: 2005
Comments: Highly commended
- Title of Thesis: Enantioselective/diasteroselective synthesis of carbocyclic and heterocyclic
compounds mediated by chiral salen-AlCl complex.
Name: C. J. Magesh
University: University of Madras
Discipline: Chemistry
Year: 2005
Comments: Highly commended
- Title of Thesis: “Snthetic applications of 2'-amino and 2'-hydroxychalcones: Synthesis of
quinolones, flavanones, chromenes, quinolines, benzofuropyridines, flavones and
pyrazolylquinolines.
Name: K. Hemanth Kumar
University: University of Madras
Discipline: Chemistry
Year: 2006
Comments: Highly commended
- Title of Thesis: Ionic Liquids Mediated Synthetic Methodologies.
Synthesis of Fulvenes and XH-14.
Name: G. Karthikeyan
University: University of Madras
Discipline: Chemistry
Year: 2006
Comments: Highly commended
- Title of Thesis: “ Eco-benign synthesis of nitrogen based heterocycles
and a new purification process”
Name: P.Arumugam
University: University of Madras
Discipline: Chemistry
Year: 2006
Comments: Highly commended
- Title of Thesis: “Synthesis of heterocycles: Indazoles, Pyrazolyldihydropyrimidines, Pyrazolybisindolylmethanes, Quinolines and Benzodiazepines”
Name G.Sivaprasad
University: University of Madras
Discipline: Chemistry
Year: 2007
Comments: Highly commended
- Title of Thesis: “Synthesis of substituted tetrahydroquinolines, indoles, C-glycosides and a
Chiron approach for Reboxetine. Oxidation of alcohols by TEMPO-Ferric Chloride hexahydrate”
Name:R.Senthilkumar
University: University of Madras
Discipline: Chemistry
Year: 2008
Comments: Highly commended
- Title of Thesis: Functionalization and applications of Baylis-Hillman bromides and
synthesis of biheterocycles
Name: Y. Zulykama
University: University of Madras
Discipline: Chemistry
Year: 2008
Comments: Highly commended
- Title of Thesis: “Synthesis of Nitrogen and Oxygen containing heterocycles using multicomponent reactions”
Name: G.Shanthi
University: University of Madras
Discipline: Chemistry
Year: 2008
Comments: Highly commended
- Title of Thesis: “Synthesis and pharmacological studies on dihydroprimidinones, bisinolylmethanes, carbazoles, Bispyrazolylmethanes and spiroxindoles”
Name: K. Sujatha
Sri Ramachandra University
Discipline: Pharmacy
Year: 2008 Comments: Highly commended
- Title of Thesis: “Synthesis of Diversely Substituted Amides and Heterocycles using nitriles”
Name: N. Panneer selvam
University: University of Madras
Discipline: Chemistry
Year: 2008
Comments: Highly commended
- Title of Thesis: “CAN mediated synthesis of novel spiro heterocyclic frameworks and palladium catalyzed synthesis of heterocyclic derivatives”
Name: G.Savitha
University: University of Madras
Discipline: Chemistry
Year: 2009
Comments: Waiting for reports
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